At2g18250 encodes pantetheine-phosphate adenylyltransferase catalyzing the formation of dephospho-CoA from pantetheine 4'-phosphate. The enzyme is involved in coenzyme A biosynthesis.
Member of a large family of putative ligands homologous to the Clavata3 gene. Consists of a single exon. It positively regulates expression of the transcription factor gene WUSCHEL-LIKE HOMEOBOX8 (WOX8)%2C and together CLE8 and WOX8 form a signaling module that promotes seed growth and overall seed size.
Plant protein of unknown function (DUF868)%3B CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF868%2C plant (InterPro:IPR008586)%3B BEST Arabidopsis thaliana protein match is: Plant protein of unknown function (DUF868) (TAIR:AT5G11000.1)%3B Has 283 Blast hits to 283 proteins in 16 species: Archae - 0%3B Bacteria - 0%3B Metazoa - 0%3B Fungi - 0%3B Plants - 283%3B Viruses - 0%3B Other Eukaryotes - 0 (source: NCBI BLink).
A member of a large family of seven-transmembrane domain proteins specific to plants%2C homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins%2C with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO4 belongs to the clade I%2C with AtMLO11 and AtMLO14. The gene is expressed during early seedling growth%2C in roots and lateral root primordia%2C in flower and fruit abscission zone%2C in vascular system of root%2C cotyledons and young leaves%2C it was not expressed in mature rosette leaves%2C as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli%2C suggesting functional redundancy%2C co-function%2C or antagonistic function(s).
vacuolar iron transporter (VIT) family protein%3B CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF125%2C transmembrane (InterPro:IPR008217)%2C Cytokine%2C IL-1-like (InterPro:IPR008996)%3B BEST Arabidopsis thaliana protein match is: Vacuolar iron transporter (VIT) family protein (TAIR:AT4G27870.1)%3B Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12%3B Bacteria - 1396%3B Metazoa - 17338%3B Fungi - 3422%3B Plants - 5037%3B Viruses - 0%3B Other Eukaryotes - 2996 (source: NCBI BLink).
Encodes a protein with R-selective hydroxynitrile lyase activity. It has similarity to the SABP2 methyl salicylate esterase from tobacco. This protein does not act on methyl IAA%2C methyl JA%2C MeSA%2C MeGA4%2C or MEGA9 in vitro.
Protein of unknown function (DUF1195)%3B CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1195 (InterPro:IPR010608)%3B BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1195) (TAIR:AT4G36660.1)%3B Has 67 Blast hits to 67 proteins in 15 species: Archae - 0%3B Bacteria - 0%3B Metazoa - 0%3B Fungi - 0%3B Plants - 67%3B Viruses - 0%3B Other Eukaryotes - 0 (source: NCBI BLink).
An alternatively spliced gene that encodes a functional transmembrane receptor serine/threonine kinase%2C alternate form may not have transmembrane domain.
Encodes a chloroplast inner envelope localized member of the Tmemb_14 gene family. FAX1 is involved in fatty acid and lipid homeostasis and likely functions as a fatty acid transporter that exports fatty acids from the plastid.
Encodes a plasodesmata-located protein involved in regulating primary root growth by controlling phloem-mediated allocation of resources between the primary and lateral root meristems.
Encodes a polygalacturonase inhibiting protein involved in defense response. PGIPs inhibit the function of cell wall pectin degrading enzymes such as those produced by fungal pathogens. PGIP1 is induced by fungal infection. Suppressed in the proton sensitive stop1-mutant%2C but the transcription level was recovered by transformation of STOP2. Knockout mutant showed severe damage in the root tip in low Ca and low pH medium.
Encodes flavanone 3-hydroxylase that is coordinately expressed with chalcone synthase and chalcone isomerases. Regulates flavonoid biosynthesis. Not responsive to auxin or ethylene stimulus (qRT-PCR).
Encodes a plastid-localized %26#945%3B-amylase. Expression is reduced in the SEX4 mutant. Loss of function mutations show normal diurnal pattern of starch accumulation/degradation. Expression follows circadian rhythms.
Encodes one of the two paralogous solanesyl diphosphate synthases - SPS1 (At1g78510) and SPS2 (At1g17050) - that assemble the side-chain of plastoquinone-9 in plastids.
Leucine-rich repeat protein kinase family protein%3B FUNCTIONS IN: protein serine/threonine kinase activity%2C kinase activity%2C ATP binding%3B INVOLVED IN: transmembrane receptor protein tyrosine kinase signaling pathway%2C protein amino acid phosphorylation%3B LOCATED IN: chloroplast%3B CONTAINS InterPro DOMAIN/s: Protein kinase%2C ATP binding site (InterPro:IPR017441)%2C Protein kinase%2C catalytic domain (InterPro:IPR000719)%2C Leucine-rich repeat-containing N-terminal domain%2C type 2 (InterPro:IPR013210)%2C Leucine-rich repeat (InterPro:IPR001611)%2C Serine/threonine-protein kinase-like domain (InterPro:IPR017442)%2C Protein kinase-like domain (InterPro:IPR011009)%2C Serine/threonine-protein kinase%2C active site (InterPro:IPR008271)%3B BEST Arabidopsis thaliana protein match is: Leucine-rich repeat protein kinase family protein (TAIR:AT3G47580.1)%3B Has 208488 Blast hits to 131556 proteins in 4837 species: Archae - 167%3B Bacteria - 21304%3B Metazoa - 66210%3B Fungi - 9769%3B Plants - 86245%3B Viruses - 308%3B Other Eukaryotes - 24485 (source: NCBI BLink).
Encodes LURP1%2C a member of the LURP cluster (late upregulated in response to Hyaloperonospora parasitica) which exhibits a pronounced upregulation after recognition of the pathogenic oomycte H. parasitica. LURP1 is required for full basal defense to H. parasitica and resistance to this pathogen mediated by the R-proteins RPP4 and RPP5.
encodes a member of glycosyl hydrolase family 1%2C located in inducible ER bodies which were formed after wounding%2C required in inducible ER body formation
Member of MAP Kinase Kinase. Likely functions in a stress-activated MAPK pathway. Can phosphorylate the MAPK AtMPK4%2C in response to stress. Gets phosphorylated by MEKK1 in response to wounding.
A single copy gene that encodes a protein with sequence similarity to tomato E8 (ACC oxidase%2C the last step in ethylene biosynthesis) involved in ethylene synthesis and fruit ripening in tomato. This gene is not induced by ethylene in siliques. The transcript is found in siliques%2C etiolated seedlings%2C leaves%2C stems and flowers.
Encodes a protein that is involved in a membrane microdomain-dependent%2C but clathrin-independent%2C endocytic pathway required for optimal seedling development.
Encodes a phosphoethanolamine/phosphocholine phosphatase. It is likely to be involved in the liberation of inorganic phosphate from intracellular sources. Expression is upregulated in the shoot of cax1/cax3 mutant.
member of MAP Kinase Kinase family. Autophosphorylates and also phosphorylates MPK3 and MPK6. Independently involved in ethylene and calmalexin biosynthesis. Induces transcription of ACS2%2C ACS6%2C ERF1%2C ERF2%2C ERF5%2C ERF6%2C CYP79B2%2C CYP79B3%2C CYP71A13 and PAD3.
Encodes a cytosolic inosine nucleoside hydrolase. Transcript levels for this gene are elevated in older leaves suggesting that it may play a role in purine catabolism during senescence.
encodes a novel Myc-related bHLH transcription factor%2C which physically associated with APRR1/TOC1 and is a member of PIF3 transcription factor family.
Encodes a member of the SPL (squamosa-promoter binding protein-like)gene family%2C a novel gene family encoding DNA binding proteins and putative transcription factors. Contains the SBP-box%2C which encodes the SBP-domain%2C required and sufficient for interaction with DNA. It is involved in regulation of flowering and vegetative phase change. Its temporal expression is regulated by the microRNA miR156. The target site for the microRNA is in the 3'UTR.
Encodes a WD-40 repeat protein similar to yeast MSI1. The predicted protein has a DWD motif. It can bind to DDB1a in Y2H assays%2C and DDB1b in co-IP assays%2C and may be involved in the formation of a CUL4-based E3 ubiquitin ligase
CRINKLY4 related 2 (CCR2)%3B FUNCTIONS IN: protein serine/threonine kinase activity%2C protein kinase activity%2C receptor activity%2C kinase activity%2C ATP binding%3B INVOLVED IN: protein amino acid phosphorylation%3B LOCATED IN: endomembrane system%3B EXPRESSED IN: 21 plant structures%3B EXPRESSED DURING: 13 growth stages%3B CONTAINS InterPro DOMAIN/s: TNFR/CD27/30/40/95 cysteine-rich region (InterPro:IPR001368)%2C Protein kinase%2C ATP binding site (InterPro:IPR017441)%2C Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245)%2C Protein kinase-like domain (InterPro:IPR011009)%2C Serine/threonine-protein kinase%2C active site (InterPro:IPR008271)%2C Regulator of chromosome condensation/beta-lactamase-inhibitor protein II (InterPro:IPR009091)%2C Protein kinase%2C catalytic domain (InterPro:IPR000719)%3B BEST Arabidopsis thaliana protein match is: CRINKLY4 related 1 (TAIR:AT3G09780.1)%3B Has 94842 Blast hits to 93551 proteins in 4006 species: Archae - 70%3B Bacteria - 8434%3B Metazoa - 36115%3B Fungi - 7540%3B Plants - 29604%3B Viruses - 210%3B Other Eukaryotes - 12869 (source: NCBI BLink).
encodes a high-affinity ammonium transporter%2C which is expressed in shoot and root. Expression in root and shoot is under nitrogen and carbon dioxide regulation%2C respectively.
encodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1%2C ATERF-2%2C AND ATERF-5.
Encodes Pht1%3B4%2C a member of the Pht1 family of phosphate transporters which include: Pht1%3B1/At5g43350%2C Pht1%3B2/At5g43370%2C Pht1%3B3/At5g43360%2C Pht1%3B4/At2g38940%2C Pht1%3B5/At2g32830%2C Pht1%3B6/At5g43340%2C Pht1%3B7/At3g54700%2C Pht1%3B8/At1g20860%2C Pht1%3B9/At1g76430 (Plant Journal 2002%2C 31:341). Expression is upregulated in the shoot of cax1/cax3 mutant and is responsive to phosphate (Pi) and not phosphite (Phi) in roots and shoots.
Predicted to be secreted protein based on signalP prediction. Involved in starch mobilization. Mutants are defective in alpha-amylase activity. (Note: AMY1 has been found in the literature to be referred to as AMY3%2C which is not to be confused with AMY3/At1g69830).
Copper transport protein family%3B FUNCTIONS IN: metal ion binding%3B INVOLVED IN: metal ion transport%3B LOCATED IN: cellular_component unknown%3B EXPRESSED IN: 11 plant structures%3B EXPRESSED DURING: 8 growth stages%3B CONTAINS InterPro DOMAIN/s: Heavy metal transport/detoxification protein (InterPro:IPR006121)%3B BEST Arabidopsis thaliana protein match is: Copper transport protein family (TAIR:AT5G52760.1)%3B Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0%3B Bacteria - 0%3B Metazoa - 736%3B Fungi - 347%3B Plants - 385%3B Viruses - 0%3B Other Eukaryotes - 339 (source: NCBI BLink).
Encodes a member of a family of F-box proteins%2C called the KISS ME DEADLY (KMD) family%2C that targets type-B ARR proteins for degradation and is involved in the negative regulation of the cytokinin response. Also named as KFB1%2C a member of a group of Kelch repeat F-box proteins that negatively regulate phenylpropanoid biosynthesis by targeting the phenypropanoid biosynthesis enzyme phenylalanine ammonia-lyase.
Encodes glutathione transferase belonging to the phi class of GSTs. Naming convention according to Wagner et al. (2002). Mutants display no pigments on leaves and stems. Likely to function as a carrier to transport anthocyanin from the cytosol to tonoplasts.
Protein of unknown function (DUF630 and DUF632)%3B FUNCTIONS IN: molecular_function unknown%3B INVOLVED IN: N-terminal protein myristoylation%3B LOCATED IN: cellular_component unknown%3B EXPRESSED IN: shoot apex%2C embryo%2C flower%3B EXPRESSED DURING: petal differentiation and expansion stage%2C D bilateral stage%3B CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF630 (InterPro:IPR006868)%2C Protein of unknown function DUF632 (InterPro:IPR006867)%3B BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF630 and DUF632) (TAIR:AT2G17110.1)%3B Has 3752 Blast hits to 2914 proteins in 298 species: Archae - 59%3B Bacteria - 209%3B Metazoa - 1260%3B Fungi - 213%3B Plants - 622%3B Viruses - 0%3B Other Eukaryotes - 1389 (source: NCBI BLink).
CONTAINS InterPro DOMAIN/s: Lipopolysaccharide-modifying protein (InterPro:IPR006598)%2C Protein of unknown function DUF821%2C CAP10-like (InterPro:IPR008539)%3B BEST Arabidopsis thaliana protein match is: Arabidopsis thaliana protein of unknown function (DUF821) (TAIR:AT3G61290.1)%3B Has 683 Blast hits to 672 proteins in 134 species: Archae - 0%3B Bacteria - 47%3B Metazoa - 230%3B Fungi - 121%3B Plants - 246%3B Viruses - 5%3B Other Eukaryotes - 34 (source: NCBI BLink).
Encodes a Cysteine-rich receptor-like kinase (CRK13). Overexpression of CRK13 leads to hypersensitive response cell death%2C and induces defense against pathogens by causing increased accumulation of salicylic acid.
GO
domain
Definition
P-value
MAPK cascade
biological_process
"An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:bf, GOC:mtg_signaling_feb11, PMID:20811974, PMID:9561267]
1.26e-06
peptide receptor activity
molecular_function
"Combining with an extracellular or intracellular peptide to initiate a change in cell activity." [GOC:jl]
2.51e-03
response to molecule of bacterial origin
biological_process
"Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin." [GOC:rl, GOC:sm]
1.84e-03
acid phosphatase activity
molecular_function
"Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum." [EC:3.1.3.2]
1.62e-02
aspartic-type endopeptidase activity
molecular_function
"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile." [ISBN:0198506732]
6.14e-03
protein kinase activity
molecular_function
"Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP." [MetaCyc:PROTEIN-KINASE-RXN]
2.21e-06
transmembrane receptor protein serine/threonine kinase activity
molecular_function
"Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [EC:2.7.11.30]
2.51e-03
plasma membrane
cellular_component
"The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363]
6.14e-03
protein phosphorylation
biological_process
"The process of introducing a phosphate group on to a protein." [GOC:hb]
9.25e-03
response to stress
biological_process
"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah]
2.63e-03
defense response
biological_process
"Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators]
2.77e-05
transmembrane receptor protein serine/threonine kinase signaling pathway
biological_process
"A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling]
2.51e-03
plasmodesma
cellular_component
"A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell." [ISBN:0198506732]
8.78e-05
response to biotic stimulus
biological_process
"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:hb]
2.59e-04
response to wounding
biological_process
"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." [GOC:go_curators]
2.30e-02
response to bacterium
biological_process
"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium." [GOC:hb]
1.01e-03
systemic acquired resistance
biological_process
"The salicylic acid mediated response to a pathogen which confers broad spectrum resistance." [GOC:lr, ISBN:052143641]
1.26e-06
salicylic acid biosynthetic process
biological_process
"The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid." [ISBN:0943088399]
2.86e-02
response to salicylic acid
biological_process
"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus." [GOC:jl]
2.58e-02
hormone-mediated signaling pathway
biological_process
"A series of molecular signals mediated by the detection of a hormone." [GOC:sm]
1.22e-03
defense response, incompatible interaction
biological_process
"A response of a plant to a pathogenic agent that prevents the occurrence or spread of disease." [GOC:lr]
"The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance." [GOC:jy]
6.14e-03
response to chitin
biological_process
"A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus." [GOC:sm]
1.75e-02
regulation of hydrogen peroxide metabolic process
biological_process
"Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide." [PMID:14765119]
2.04e-03
regulation of plant-type hypersensitive response
biological_process
"Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response." [PMID:16255244]
2.58e-02
negative regulation of defense response
biological_process
"Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." [GOC:mah]
2.55e-02
ubiquitin protein ligase binding
molecular_function
"Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins." [GOC:vp]
5.00e-03
response to endoplasmic reticulum stress
biological_process
"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." [GOC:cjm, GOC:mah]
1.74e-02
defense response to bacterium
biological_process
"Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism." [GOC:jl]
8.78e-04
response to external biotic stimulus
biological_process
"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." [GOC:go_curators]
4.28e-04
protein autophosphorylation
biological_process
"The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation)." [ISBN:0198506732]
4.26e-05
response to stimulus
biological_process
"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf]
6.55e-04
response to other organism
biological_process
"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." [GOC:ai]
4.28e-04
defense response to other organism
biological_process
"Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos]
